NMN
NMN Powder | β-Nicotinamide Mononucleotide Manufacturer Headline: Premium NMN (β-Nicotinamide Mononucleotide) Manufacturer | 99.9% Purity (CAS: 1094-61-7) Sub-info: Grade: Pharmaceutical / Food Grade | Assay: ≥99% (HPLC) | Strategy: Full Enzymatic Catalysis USP: High Density (0.6-0.8 g/mL) • High Stability (24 Months) • Third-Party Lab Tested
Introduction
β-Nicotinamide Mononucleotide (NMN) is a bioactive nucleotide and the direct precursor to Nicotinamide Adenine Dinucleotide (NAD+), a basic coenzyme found in each living cell. Not at all like Nicotinamide Riboside (NR), NMN enters the NAD+ rescue pathway specifically, making it the most productive booster for cellular vitality and DNA repair.
Our NMN is created utilizing a exclusive Green Enzymatic Strategy (not chemical synthesis), guaranteeing a Beta-Isomer structure that is safe, natural, and free from organic solvent residues.
Category：
Keywords：
natural
rosmarinic
preservative
Functions
1. NAD+ Level Rebuilding (Anti-Aging)
NAD+ levels decay by up to 50% as we age, leading to mitochondrial dysfunction. Oral supplementation with NMN effectively replenishes NAD+ pools, activating Sirtuins (longevity genes) to repair damaged DNA and slow cellular aging.
2. Mitochondrial Energy Boost (ATP)
By increasing NAD+, NMN enhances the efficiency of the Electron Transport Chain in mitochondria, improving ATP production. This results in increased physical endurance, reduced fatigue, and improved muscle function in older adults.
3. Cognitive & Metabolic Support
Studies indicate NMN improves insulin sensitivity and supports neuroprotection, potentially delaying age-related cognitive decline and improving metabolic markers.
Applications
Dietary Supplements:
• Capsules: Our High-Density Powder (>0.6 g/mL) allows you to fill 500mg into a smaller size #0 capsule, reducing production costs and improving consumer swallowing experience.
• Sublingual Tablets: High solubility makes it ideal for fast-dissolving lozenges.
Cosmetics:
• Anti-Aging Serums: Used to boost skin cell turnover and repair UV damage.
Functional Foods:
• Stable enough for beverage fortification (when pH is controlled).
Flow Chart
Raw Material Preparation (Nicotinamide + Ribose) → Enzymatic Catalysis (Specific Enzyme) → Reaction Termination → Filtration → Purification (Ion Exchange) → Concentration → Crystallization → Centrifugation → Vacuum Drying → Milling (Particle Size Control) → Quality Control (HPLC/NMR) → Packaging
Note: Our enzymatic process operates at room temperature/neutral pH, avoiding the toxic impurities associated with chemical synthesis methods.
Quality Standard of Lactoferrin
| Item | Specification | Result |
| Appearance | White to off-white crystalline powder | Conforms |
| Assay (HPLC) | ≥ 99.0% (Anhydrous Basis) | 99.8% |
| pH (1% Solution) | 3.0 – 4.0 | 3.4 |
| Water Content | ≤ 1.0% | 0.3% |
| Bulk Density (Tapped) | ≥ 0.6 g/mL (High Density) | 0.72 g/mL |
| Heavy Metals (Pb) | ≤ 0.5 ppm | < 0.1 ppm |
| Arsenic (As) | ≤ 0.5 ppm | < 0.1 ppm |
| Microbiology | ≤ 1,000 cfu/g | < 100 cfu/g |
| Ethanol Residue | ≤ 5,000 ppm | Not Detected |
Method of Analysis of Lactoferrin
We use High-Performance Liquid Chromatography (HPLC) to verify purity.
• Chiral Specificity: We also employ H-NMR (Proton Nuclear Magnetic Resonance) to confirm the structure is exclusively the biologically active Beta-form, with zero Alpha-form contamination.
Reference Chromatogram of Lactoferrin Reference Substance
(Imagine a pristine HPLC graph)
The chromatogram shows a single dominant peak at the retention time of β-NMN (approx. 5-6 min). No impurity peaks are observed, confirming the absence of Nicotinamide or other degradation byproducts.
Stability and Safety
Stability Studies
Early NMN products were unstable. Our optimized crystallization technology has solved this.
• Shelf Life: 24 months.
• Stress Test: Samples stored at 40°C/75% RH (Accelerated Conditions) for 6 months showed <1% degradation.
• Storage: Store in a cool, dry place. While our powder is stable at room temperature, we recommend cold storage (2-8°C) for long-term warehousing to maintain peak potency.
Safety & Handling (MSDS Summary)
• Classification: Non-hazardous.
• Handling: Wear standard PPE (mask, gloves).
• Storage: Keep container tightly closed. Avoid moisture (NMN can hydrolyze into Nicotinamide in water over time).
Customer Comments
Production Manager, US Supplement Brand
2026.02.11
★★★★★
Sourcing Director, German Nutraceutical Co.
2026.02.11
★★★★★
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FAQ
What is the difference between Synthetic and Enzymatic NMN?
Synthetic NMN uses organic solvents and may contain chemical impurities. Enzymatic NMN (our method) mimics the body's natural production, resulting in higher purity, a greener footprint, and a safer product profile.
Why is Bulk Density important for NMN?
High Density (0.6-0.8 g/mL) powder is less dusty and occupies less volume. This allows you to fit higher dosages (e.g., 500mg) into smaller capsules, which consumers prefer. Low-density "fluffy" NMN often requires large, hard-to-swallow capsules.
Does NMN need to be refrigerated?
Our stabilized crystalline form is stable at room temperature (25°C) for shipping and short-term storage. However, to maximize shelf life (2 years+), we recommend keeping the raw material in a cool place or refrigerator (2-8°C), especially after opening.
References
1.Mills, K. F., et al. "Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice." Cell Metabolism (2016).
2.Yoshino, J., et al. "Nicotinamide mononucleotide, a key NAD+ intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice." Cell Metabolism (2011).
3.Irie, J., et al. "Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men." Endocrine Journal (2020).
4.Gomes, A. P., et al. "Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging." Cell (2013).
5.Poddar, S. K., et al. "Nicotinamide Mononucleotide: Exploration of Diverse Therapeutic Applications of a Potential Molecule." Biomolecules (2019).
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