D-Raffinose pentahydrate
D-Raffinose Pentahydrate | Premium Prebiotic & Excipient Headline: High-Purity D-Raffinose Pentahydrate Manufacturer | 99% Crystalline (CAS: 17629-30-0) Sub-info: Source: Characteristic Plant Extraction (Cottonseed/Beet) | Non-GMO | Assay: ≥99.0% USP: Effective Bifidogenic Figure • Organ Conservation Review • Great Stability
Introduction
D-Raffinose Pentahydrate is a normal trisaccharide composed of galactose, glucose, and fructose. It is classified as a useful oligosaccharide with solid prebiotic properties. Not at all like basic sugars, it is unpalatable by human proteins and comes to the colon intaglio, where it specifically bolsters advantageous microscopic organisms (Bifidobacteria and Lactobacilli).
Beyond sustenance, our high-purity crystalline Raffinose is a basic component in Organ Conservation Arrangements (like UW Arrangement) due to its predominant osmotic properties and capacity to avoid cellular edema amid hypothermic storage.
Category：
Keywords：
d-raffinose
pentahydrate
Functions
1.Prebiotic & Intestine Health
Raffinose is a powerful "Bifidus Calculate." Clinical considers appear that ingesting little sums advances the expansion of useful intestine vegetation, makes strides bowel normality, and restrains the development of hurtful microbes like Clostridium perfringens, in this manner lessening intestinal toxins.
2.Cryoprotection & Cell Preservation
In the pharmaceutical and therapeutic areas, Raffinose is utilized as a cryoprotectant. It stabilizes cell films and proteins amid freeze-drying (lyophilization) and low-temperature capacity, making it basic for protecting antibodies, stem cells, and transplant organs.
3.Skin Moisturizing (Cosmetics)
Its special crystalline structure ties water atoms viably. When utilized in makeup, it gives profound hydration and underpins the skin obstruction work without the stickiness related with glycerin.
Applications
Medical & Pharmaceutical:
• Organ Conservation Solutions: A key osmotic operator in UW (University of Wisconsin) solution for liver/kidney transplants.
• Vaccine Stabilizer: Protects biological activity during lyophilization.
Functional Foods:
• Prebiotic Supplements: Low-calorie fiber source for intestine wellbeing powders.
• Anti-Allergy Nourishments: A few thinks about recommend it makes a difference tweak the safe framework (Th1/Th2 adjust) to reduce atopic dermatitis.
Cosmetics:
• Moisturizers: Utilized in high-end creams for its non-tacky humectant properties.
Flow Chart
Raw Material (Cottonseed Meal) → Extraction (Water/Ethanol) → Filtration → Decolorization (Activated Carbon) → Ion Exchange (Demineralization) → Concentration → Chromatographic Separation (Purification) → Crystallization → Centrifugation → Drying → Sieving → Packaging
Note: Our refinement prepare expels potential allergens (gossypol) to non-detectable levels.
Quality Standard of Lactoferrin
| Item | Specification | Result |
| Appearance | White or almost white powder | Conforms |
| Assay (HPLC) | ≥ 98.0% | 99.4% |
| Specific Rotation | +103.0° to +108.0° | +105.2° |
| Loss on Drying | 13.0% - 17.0% (Pentahydrate) | 15.1% |
| Residue on Ignition | ≤ 0.1% | 0.03% |
| Heavy Metals | ≤ 10 ppm | < 5 ppm |
| Arsenic (As) | ≤ 1.0 ppm | < 0.2 ppm |
| Microbiology | ≤ 1,000 cfu/g | < 50 cfu/g |
| Endotoxin | < 0.25 EU/mg (For Pharma Grade) | Conforms |
Method of Analysis of Lactoferrin
We utilize HPLC with Refractive List (RI) Location to guarantee accurate quantification of Raffinose and separation from other sugars like Sucrose or Stachyose.
• Water Content: We entirely control the pentahydrate water of crystallization (approx 15%) to guarantee gem stability.
Reference Chromatogram of Lactoferrin Reference Substance
(Imagine a clean HPLC graph)
The chromatogram shows a single sharp crest for Raffinose. Debasements like Melibiose or Sucrose are ordinarily underneath 0.5%, assembly the exacting necessities for pharmaceutical applications.
Stability and Safety
Stability Studies
• Shelf Life: 36 months (3 Years).
• Conditions: Chemically steady beneath unbiased pH. Does not take part in Maillard response (non-reducing sugar), meaning it won't turn brown in formulations.
• Storage: Store in a cool, dry put. Crystalline shape is moderately steady against mugginess compared to undefined sugars.
Safety & Handling (MSDS Summary)
• Classification: Food Ingredient / GRAS.
• Safety: Non-toxic. Excessive consumption (>15g/day) may cause transient flatulence due to fermentation in the gut.
• Handling: Standard food/pharma hygiene.
Customer Comments
Lab Chief, US Biotech Company
2026.02.13
★★★★☆
Item Supervisor, Japanese Utilitarian Nourishment Brand
2026.02.13
★★★★☆
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FAQ
What is "Pentahydrate"?
It implies each atom of Raffinose is related with 5 water atoms in its gem structure. This is the steady, normal frame of Raffinose (CAS 17629-30-0). The anhydrous frame is exceptionally hygroscopic and unstable.
Is Raffinose a sugar? Does it spike blood sugar?
Chemically, it is a trisaccharide sugar. Be that as it may, people need the protein (alpha-galactosidase)to process it. Subsequently, it does not cause a quick spike in blood glucose and is considered secure for diabetics (moo glycemic index).
Can it be utilized in skincare?
Yes. It is an amazing moisturizer. Not at all like polyols (glycerin), it is not sticky indeed at tall mugginess. It moreover makes a difference stabilize lamellar structures in emulsions.
References
1.Tomomatsu, H. "Health effects of oligosaccharides." Food Technology (1994).
2.Ben, S., et al. "Raffinose: Sources, processing and health benefits." Journal of Functional Foods.
3.Southard, J. H., & Belzer, F. O. "Organ preservation." Annual Review of Medicine (1995) (Reference for UW Solution).
4.Nagai, Y., et al. "Characterization of the prebiotic effect of raffinose on gut microbiota." Bioscience, Biotechnology, and Biochemistry.
5.Kikuchi, H., et al. "Cosmetic applications of raffinose." Journal of Applied Glycoscience.
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