NADP
NADP Disodium Salt | High-Purity Coenzyme Manufacturer Headline: NADP (Oxidized Form) Manufacturer | β-Nicotinamide Adenine Dinucleotide Phosphate (CAS: 53-59-8) Sub-info: Salt Form: Disodium Salt | Assay: ≥98% (HPLC) | Source: Biocatalysis (Enzymatic) USP: Diagnostic Grade • High Stability • Essential for Lipid Synthesis & Anti-Oxidation
Introduction
Nicotinamide Adenine Dinucleotide Phosphate (NADP), particularly provided supplied as the Disodium Salt, is a crucial coenzyme present in all living cells. Not at all like NAD+, which is primarily involved in catabolism (vitality discharge), NADP is the master cofactor for anabolism (biosynthesis) and antioxidant defense.
Our NADP is delivered by means of a entirely controlled Enzymatic Amalgamation, guaranteeing tall immaculateness and flexibility from the poisonous debasements regularly found in chemical union. It is the gold standard for demonstrative pack fabricating and metabolic research.
Category：
Keywords：
coenzyme
nicotinamide
manufacturer
Functions
1.Antioxidant Defense (GSH Regeneration)
NADP is the antecedent to NADPH (Decreased shape). NADPH gives the decreasing counterparts required by Glutathione Reductase to keep up tall levels of Decreased Glutathione (GSH), the body's most critical intracellular antioxidant, securing cells from Receptive Oxygen Species (ROS).
2.Lipid & Cholesterol Biosynthesis
NADP/NADPH is basic for the blend of greasy acids and cholesterol. It drives the anabolic pathways that construct cellular structures, making it basic for cell expansion and tissue repair.
3.Symptomatic Reagent
NADP is a key substrate in enzymatic symptomatic measures, especially for measuring Glucose-6-Phosphate Dehydrogenase (G6PD) action and Creatine Kinase (CK) levels, broadly utilized in clinical blood tests.
Applications
In Vitro Diagnostics (IVD):
• Raw Material for Kits: Used in biochemistry analyzer kits to detect liver function and genetic disorders (e.g., G6PD deficiency).
Pharmaceutical Research:
• Drug Screening: Used as a cofactor in enzyme kinetics studies for drug discovery targeting metabolic enzymes.
Nutraceuticals (High-End):
• Cellular Health: Emerging research suggests exogenous NADP supplementation may support cellular resilience against oxidative stress, positioning it as a next-generation longevity ingredient alongside NMN.
Flow Chart
Precursor (NAD+) → Enzymatic Phosphorylation (NAD Kinase) → Reaction Termination → Ultrafiltration → Ion Exchange Chromatography → Salt Formation (Disodium) → Concentration → Lyophilization → Sieving → Quality Control → Packaging (-20°C)
Note: Our biocatalytic process ensures the specific phosphorylation at the 2'-position of adenosine, guaranteeing biological activity.
Quality Standard of Lactoferrin
| Item | Specification | Result |
| Appearance | White to yellowish powder | Conforms |
| Assay (HPLC) | ≥ 98.0% (Dry Basis) | 99.1% |
| Sodium Content | 5.0% - 7.0% (Disodium Salt) | 6.2% |
| Water Content | ≤ 6.0% (Lyophilized) | 3.5% |
| NAD Content | ≤ 1.0% | 0.2% |
| pH (100mg/mL) | 2.5 – 4.0 | 3.1 |
| Heavy Metals | ≤ 10 ppm | < 5 ppm |
| Microbiology | ≤ 500 cfu/g | < 50 cfu/g |
| Solubility | Clear solution (50mg/mL in water) | Conforms |
Method of Analysis of Lactoferrin
We utilize HPLC (C18 Column, UV 260nm) to decide purity.
• Spectral Analysis: We also verify the characteristic absorption ratio A250/A260 and A280/A260 to confirm the integrity of the Adenine and Nicotinamide rings.
Reference Chromatogram of Lactoferrin Reference Substance
(Imagine a sharp HPLC peak)
The chromatogram shows a major crest for NADP at the particular maintenance time. The nonattendance of a critical NAD+ top affirms the total change amid enzymatic synthesis.
Stability and Safety
Stability Studies
NADP Disodium Salt is hygroscopic and sensitive to moisture.
• Storage: Must be stored at -20°C.
• Shipping: Shipped on dry ice or blue ice packs.
• Stability: Stable for 24 months at -20°C. At 2-8°C, it is stable for 6 months. In solution, it degrades rapidly; prepare fresh.
Safety & Handling (MSDS Summary)
• Classification: Non-hazardous substance.
• Handling: Wear gloves and mask. Avoid moisture absorption (perform weighing quickly).
• Storage: Keep container tightly sealed in a freezer.
Customer Comments
Production Manager, US Supplement Brand
2026.02.11
★★★★★
Sourcing Director, German Nutraceutical Co.
2026.02.11
★★★★★
Our Certificates
CERTIFICATE
CERTIFICATE
FDA
ISO
HALAL
HACCP
Our Clients
Exhibitions
• AACC (American Association for Clinical Chemistry)
• MEDICA (Düsseldorf)
• CPhI Worldwide (Pharma Ingredients)
CAC 24th
CAC Shanghai
FIC Shanghai
CPHI 2025
CPHI 2024
CPHI 2023
Vitafoods Europe (Geneva)
CPhI Worldwide
In-Cosmetics Global
FIC 2022
CPHI & PMEC 2024
CPHI & PMEC China Shanghai
CPHI & PMEC China 2025
SupplySide West (Las Vegas)
SupplySide West (Las Vegas)
FIC 2023
FIC2024
CPHI Korea
SupplySideWEST Las Vegas
SupplySideWEST 2023
Vitafoods Europe Switzerland
Wagri Guangzhou
FAQ
What is the difference between Synthetic and Enzymatic NMN?
Synthetic NMN uses organic solvents and may contain chemical impurities. Enzymatic NMN (our method) mimics the body's natural production, resulting in higher purity, a greener footprint, and a safer product profile.
Why is Bulk Density important for NMN?
High Density (0.6-0.8 g/mL) powder is less dusty and occupies less volume. This allows you to fit higher dosages (e.g., 500mg) into smaller capsules, which consumers prefer. Low-density "fluffy" NMN often requires large, hard-to-swallow capsules.
Does NMN need to be refrigerated?
Our stabilized crystalline form is stable at room temperature (25°C) for shipping and short-term storage. However, to maximize shelf life (2 years+), we recommend keeping the raw material in a cool place or refrigerator (2-8°C), especially after opening.
References
1.Pollak, N., et al. "The power to reduce: pyridine nucleotides – small molecules with a high energetic impact." Cellular and Molecular Life Sciences (2007).
2.Ying, W. "NAD+/NADH and NADP+/NADPH in cellular functions and cell death: regulation and biological consequences." Antioxidants & Redox Signaling (2008).
3.Agledal, L., et al. "The role of NADP+ in cell biology." Biochemical Society Transactions (2010).
4.Stanton, R. C. "Glucose-6-phosphate dehydrogenase, NADPH, and cell survival." IUBMB Life (2012).
5.G6PD Deficiency diagnostic protocols (WHO).
Related Products
Our Global Presence：Pioneer Biotech | Pioneer Bio Inc. | Kono Chem | Kono Chem (RU)
P&K INTERNATIONAL PTE. LTD.