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Seabuckthorn flavone

Sea Buckthorn Flavone Manufacturer | 40% Standardized Extract CAS: 90106-68-6 | Potent Bio-flavonoids for Cardiovascular Health Source: Hippophae rhamnoides (Wild-Harvested) | Specs: 10% - 40% UV Certifications: ISO9001, HACCP, Halal, Kosher, Organic Source • Cardio-Protective: Rich in Isorhamnetin and Quercetin, clinically recognized for supporting heart function. • High Potency: Concentrated extract containing ≥40% Total Flavones. • Clean Extraction: Water/Ethanol extraction ensures no toxic residues. • Supply: Ready Stock in Xi'an/Shanghai | Fast Dispatch (7 Days).

Introduction


P&K

Sea Buckthorn Flavone is a bioactive complex extracted primarily from the fruit residue or leaves of the Sea Buckthorn plant (Hippophae rhamnoides). While the oil is famous for Omega-7, the Flavones are the water-soluble powerhouse of this superfood.

Our product acts as a powerful antioxidant and circulatory aid. It contains a unique spectrum of flavonols, with Isorhamnetin, Quercetin, and Kaempferol being the three major aglycones. This profile makes it distinct from other flavonoid sources like Ginkgo or Hawthorn, offering specialized benefits for myocardial health and hypoxia tolerance.

 

Category:

Keywords:

extraction

isorhamnetin

rhamnoides

Functions


1. Cardiovascular Health (Key USP)

• Anti-Angina: Clinically utilized to alleviate angina pectoris by improving coronary blood flow and reducing myocardial oxygen consumption.

• Microcirculation: Enhances capillary strength and reduces blood viscosity, promoting healthy circulation to extremities and vital organs.

2. Lipid Metabolism

• Cholesterol Control: Studies indicate that Sea Buckthorn Flavones inhibit the oxidation of LDL cholesterol and may help lower total serum cholesterol and triglycerides.

3. Antioxidant & Immune Support

• Free Radical Scavenger: Exhibits strong superoxide anion scavenging activity, protecting cells from oxidative stress and slowing cellular aging.

• Immune Modulation: Supports the body's natural defense mechanisms against environmental stressors.

Applications


Pharmaceuticals & TCM:

• Heart Health Drugs: Key raw material for proprietary medicines treating ischemic heart disease and hyperlipidemia.

Dietary Supplements:

• Circulation Formulas: Capsules targeting blood pressure support and vascular health.

• Antioxidant Blends: Often combined with Vitamin C (naturally abundant in Sea Buckthorn) for synergistic immune support.

Functional Foods:

• Beverage Additives: Water-soluble grades available for functional health drinks.

Cosmetics:

• Anti-Aging Creams: Used for its ability to scavenge free radicals and improve skin microcirculation (rosy complexion).

Flow Chart


1.Raw Material: Selection of dried Sea Buckthorn fruit residue (pomace) or leaves.

2.Extraction: Reflux extraction with Ethanol/Water solution.

3.Filtration: Separation of solid plant fibers.

4.Concentration: Vacuum evaporation to recover solvent.

5.Purification (Macroporous Resin): Critical step to enrich Total Flavones to 40% and remove sugars/acids.

6.Spray Drying: Conversion to fine brownish-yellow powder.

7.Sieving (80 Mesh): Ensuring uniform particle size.

8.Testing: UV analysis for Total Flavones content.

Quality Standard of Lactoferrin


Product: Sea Buckthorn Flavone 40%

ItemSpecificationResult
AppearanceBrown to brownish-yellow fine powderConforms
OdorCharacteristic, slight astringent tasteConforms
Total Flavones (UV)≥ 40.0% (as Rutin)42.1%
IsorhamnetinIdentification PositiveConforms
Loss on Drying≤ 5.0%3.6%
Ash≤ 5.0%2.8%
Heavy Metals (Pb)≤ 2.0 ppm0.5 ppm
Arsenic (As)≤ 1.0 ppmNot Detected
MicrobiologyTotal Plate Count < 1000 CFU/gConforms

Note: Lower specs (10%, 20%) are also available for general food use.

Method of Analysis of Lactoferrin


UV-Vis Spectrophotometry is the industry standard for "Total Flavones of Sea Buckthorn".

• Reference Standard: Rutin.

• Method: Colorimetric reaction with Aluminum Nitrate / Sodium Nitrite.

• HPLC: Can be used for specific profiling of Isorhamnetin, Quercetin, and Kaempferol upon request.

Reference Chromatogram of Lactoferrin Reference Substance


(Image Placeholder: HPLC Fingerprint of Sea Buckthorn Flavones)

The chromatogram displays three distinct major peaks corresponding to Isorhamnetin, Quercetin, and Kaempferol. The ratio of Isorhamnetin is typically higher in Sea Buckthorn compared to other flavonoid sources, serving as a marker for authenticity.

Stability and Safety


Stability Studies

• Sensitivity: Flavonoids are sensitive to oxidation and humidity.

• Storage: Must be stored in tightly sealed, light-resistant containers (e.g., aluminum foil bags) in a cool, dry place.

• Shelf Life: 24 months.

Safety & Handling (MSDS Summary)

• Classification: Non-hazardous botanical ingredient.

• Safety: Generally recognized as safe. No specific toxicity reported at recommended dosages.

• Contraindications: Due to its blood-thinning properties, consult a physician if taking anticoagulants (Warfarin).

Long-term stability testing of Sea Buckthorn Flavone

MSDS of Sea Buckthorn Flavone

Customer Comments


QC Manager, Pharma Manufacturer, Russia

QC Manager, Pharma Manufacturer, Russia

2026.02.06

★★★★☆

"Pioneer's 40% extract is the most potent we've tested. The Isorhamnetin peak is clearly visible in our HPLC verification."
Product Developer, Herbal Tea Brand, UK

Product Developer, Herbal Tea Brand, UK

2026.02.06

★★★★☆

"We use this in our 'Heart Care' tea blend. It dissolves reasonably well and adds a nice functional claim."

Our Certificates


CERTIFICATE

CERTIFICATE

CERTIFICATE

CERTIFICATE

FDA

FDA

ISO

ISO

HALAL

HALAL

HACCP

HACCP

Our Clients


Abbott
Big Bear Pharmaceuticals
Spring season
HIEIDO
Oil and Fat Corporation
Dalian University
China Pharmaceutical University
Shenyang Pharmaceutical University
SIOC
SIMM
KANS
Renhe Pharmaceutical
JNJ
HANHOO
Korea University
Kyeonggi University
LG
Samyang Foods
AJINOMOTO
PipingRock‌
DSM-Firmenich
Beijing Tongrentang
Nestlé
BIOHIGH
Evonik Industries
Herbalife Nutrition
L'ORÉAL
STARFIELD
Unilever
MERCK

Exhibitions


• CPhI Worldwide (Pharma Ingredients)

• SupplySide West (Las Vegas)

• Vitafoods Europe

In-Cosmetics Global

In-Cosmetics Global

SupplySide West (Las Vegas)

SupplySide West (Las Vegas)

SupplySide West (Las Vegas)

SupplySide West (Las Vegas)

Vitafoods Europe (Geneva)

Vitafoods Europe (Geneva)

CPhI Worldwide

CPhI Worldwide

FIC Shanghai

FIC Shanghai

FIC2024

FIC2024

CPHI Korea

CPHI Korea

SupplySideWEST Las Vegas

SupplySideWEST Las Vegas

SupplySideWEST 2023

SupplySideWEST 2023

Vitafoods Europe Switzerland

Vitafoods Europe Switzerland

Wagri Guangzhou

Wagri Guangzhou

CPHI & PMEC China 2025

CPHI & PMEC China 2025

CAC 24th

CAC 24th

CAC Shanghai

CAC Shanghai

CPHI & PMEC 2024

CPHI & PMEC 2024

CPHI & PMEC China Shanghai

CPHI & PMEC China Shanghai

CPHI 2025

CPHI 2025

CPHI 2024

CPHI 2024

CPHI 2023

CPHI 2023

FIC 2022

FIC 2022

FIC 2023

FIC 2023

FAQ


What is the main difference between Sea Buckthorn Oil and Flavone?

• Oil: Lipid-soluble. Rich in Omega-7. Best for skin, mucosa, and ulcers. • Flavone: Water-soluble (extract). Rich in bioflavonoids. Best for heart health, circulation, and blood pressure.

Is the source sustainable?

Yes. Our Sea Buckthorn is wild-harvested or sourced from sustainable plantations in the high-altitude regions of China (Inner Mongolia/Shanxi), where it is grown to prevent desertification. It is an eco-friendly crop.

What is the recommended dosage?

For the 40% extract, typical dosages range from 150mg to 300mg per day for general cardiovascular support.

References


1.Eccleston, C., et al. (2002). Effects of an antioxidant-rich juice (sea buckthorn) on risk factors for coronary heart disease in humans. Journal of Nutritional Biochemistry.

2.Pang, X., et al. (2008). Antihypertensive effect of total flavones extracted from seed residues of Hippophae rhamnoides L. in sucrose-fed rats. Journal of Ethnopharmacology.

3.Zhang, X., et al. (2005). Effect of total flavones of Hippophae rhamnoides L. on sympathetic activity in hypertension. Journal of Chinese Integrative Medicine.

4.Suryakumar, G., & Gupta, A. (2011). Medicinal and therapeutic potential of Sea buckthorn (Hippophae rhamnoides L.). Journal of Ethnopharmacology.

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