Raspberry ketone glucoside
Raspberry Ketone Glucoside | Advanced Skin Whitening Agent Headline: High-Purity Raspberry Ketone Glucoside Manufacturer | 98% Skin Brightening Agent (CAS: 38963-94-9) Sub-info: Assay: ≥98% (HPLC) | Appearance: White Crystalline Powder | Source: Enzymatic Glycosylation USP: Potent Tyrosinase Inhibitor • Nitric Oxide Scavenger • Superior Stability vs.
Introduction
Raspberry Ketone Glucoside, also known as 4-(4-Hydroxyphenyl)-2-butanone 4'-O-β-D-glucoside, is a stable, water-soluble derivative of the natural aromatic compound Raspberry Ketone. By attaching a glucose molecule, we significantly enhance its stability and bioavailability in cosmetic formulations.
It is a breakthrough anti-aging and whitening ingredient that effectively inhibits melanin synthesis and scavenges nitric oxide (NO), preventing oxidative skin damage caused by UV radiation and environmental pollution.
Raspberry ketone glucoside is a natural plant-derived compound obtained from high-quality raspberries using advanced extraction and purification technologies. It is a water-soluble glycoside with excellent stability and consistent purity, making it suitable for incorporation into a variety of industrial and commercial formulations. The product is produced under strict quality control standards to ensure batch-to-batch consistency, free from contaminants, and compliant with international safety and quality regulations.
Raspberry ketone glucoside is offered as a fine powder with uniform particle size, allowing easy handling, blending, and formulation into powders, liquids, or encapsulated products. Its excellent solubility and stability make it compatible with diverse manufacturing processes, including spray-drying, mixing, and encapsulation. This versatility ensures that it can be used in nutritional, food, beverage, and cosmetic formulations where a high-quality plant-derived ingredient is required.
The product is stored under recommended conditions to maintain its stability and prevent moisture absorption, and it is packaged in sealed, food-grade containers to preserve quality during transportation and storage. Sourcing is traceable, and all production stages are documented to meet regulatory requirements.
Raspberry ketone glucoside is increasingly sought after by manufacturers and formulators who require reliable, high-purity plant-derived ingredients that are easy to handle, store, and integrate into commercial production. Its consistent quality and versatility make it a practical choice for ingredient suppliers, contract manufacturers, and research institutions looking for standardized natural compounds.
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raspberry
ketone
glucoside
Raspberry ketone glucoside
Functions
1. Potent Skin Whitening (Tyrosinase Inhibition)
Raspberry Ketone Glucoside works by inhibiting the activity of tyrosinase, the rate-limiting enzyme in melanin production. It effectively reduces hyperpigmentation, dark spots, and uneven skin tone, delivering a brighter complexion.
2. Nitric Oxide (NO) Scavenging
Excessive Nitric Oxide in the skin (induced by UV rays) leads to inflammation and aging ("inflamm-aging"). This glucoside is a superior NO scavenger, neutralizing free radicals and protecting skin cells from oxidative stress and roughness.
3. Anti-Aging & Skin Conditioning
It promotes skin metabolism and improves skin texture. Unlike harsh whitening agents like Hydroquinone, it is gentle and non-irritating, making it suitable for long-term use in anti-aging serums and creams.
Applications
Whitening & Brightening:
• Spot Correctors: Targets age spots and melasma.
• Brightening Creams: For overall skin tone improvement.
Anti-Aging Skincare:
• Day Creams: Protects against UV-induced inflammation.
• Repair Serums: Soothes skin and reduces redness.
Formulation Advantage:
• High Solubility: Much more soluble in water than pure Raspberry Ketone, making it easier to formulate into clear lotions and essences.
Flow Chart
Raspberry Ketone Preparation → Enzymatic Glycosylation (Biocatalysis) → Extraction → Filtration → Purification (Column Chromatography) → Concentration → Crystallization → Recrystallization (For 98% Purity) → Drying → Milling → Quality Control (HPLC) → Packaging
Note: Our enzymatic process ensures specific beta-glycosidic linkage, guaranteeing biological activity and purity.
Quality Standard of Lactoferrin
Item | Specification | Result |
Appearance | White or almost white crystal powder | Complies |
Specific Rotation | -55°~ -59° | -56.4° |
Clarity of solution | 3% water solution should clarifying | Complies |
PH | 5.0-7.0 | 6.5 |
Loss on drying | ≤1.0% | 0.1% |
Ignition residue | ≤0.1% | 0.05% |
Heavy metals | ≤0.002% | Complies |
Content | ≥98.0% | 99.3% |
Conclusion: | The product complies with Enterprise Standard | |
Method of Analysis of Lactoferrin
We use HPLC (High-Performance Liquid Chromatography) with UV detection to quantify the glucoside content.
• Purity Verification: We ensure the absence of free Raspberry Ketone (aglycone) and glucose impurities, confirming the complete glycosylation structure.
Reference Chromatogram of Lactoferrin Reference Substance
The chromatogram displays a single major peak for Raspberry Ketone Glucoside. No significant impurity peaks are observed, ensuring high purity and safety for cosmetic use.
Stability and Safety
Stability Studies
• Shelf Life: 24 months.
• Thermal Stability: Stable at temperatures up to 80°C during formulation.
• pH Stability: Stable in a wide pH range (4.0 - 8.0).
• Storage: Store in a cool, dry place. Keep container tightly closed to prevent moisture absorption.
Safety & Handling (MSDS Summary)
• Classification: Non-hazardous cosmetic ingredient.
• Irritation: Patch tests show no primary skin irritation at recommended dosage (0.5% - 2.0%).
• Handling: Wear standard PPE (mask, gloves).
Customer Comments
Formulation Chemist, Japanese Cosmetic Brand
2026.02.04
★★★★☆
R&D Manager, US Skincare Lab
2026.02.04
★★★★☆
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FAQ
How is it different from Raspberry Ketone?
Raspberry Ketone is oil-soluble and volatile. Raspberry Ketone Glucoside is water-soluble, non-volatile, and much more stable against oxidation. The glucoside form releases the active ketone slowly in the skin, reducing irritation and prolonging the effect.
What is the recommended usage rate?
For skin whitening and anti-aging products, we recommend 0.5% - 3.0%. It can be added to the water phase of the formulation.
Is it natural?
It is a nature-identical derivative produced via enzymatic glycosylation, which mimics the natural process found in plants. It is considered a safe and effective cosmetic ingredient.
References
1.Harada, N., et al. "Inhibitory effect of raspberry ketone glucoside on melanin synthesis." Journal of Cosmetic Science.
2.Morimoto, C., et al. "Anti-obese action of raspberry ketone." Life Sciences (Context on parent molecule).
3.Pillaiyar, T., et al. "Skin whitening agents: medicinal chemistry perspective of tyrosinase inhibitors." Journal of Enzyme Inhibition and Medicinal Chemistry (2017).
4.Cosmetic Ingredient Review (CIR). "Safety Assessment of Ketones as Used in Cosmetics."
5.Lin, J.W., et al. "Antioxidant activity of raspberry extract." Food Chemistry.
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