Sodium Ribonucleic Acid
Sodium Ribonucleic Acid Manufacturer | Immune Booster & Cellular Repair (CAS: 9009-85-2) Source: Saccharomyces cerevisiae (Yeast) | Purity: 85.0% (Enzymatic Method) | Certifications: ISO9001, HACCP, Halal, Kosher High Nucleotide Content | Non-GMO Yeast Origin | Ready Stock in Local Warehouse
Introduction
Sodium Ribonucleic Acid (Sodium RNA; CAS: 9009-85-2) is a biologically active macromolecule extracted from high-quality food-grade yeast (Saccharomyces cerevisiae). Through controlled fermentation and advanced separation technologies, we obtain a high-purity sodium salt form of RNA that is water-soluble and highly bioavailable.
As a rich source of dietary nucleotides, Sodium RNA plays a pivotal role in cellular regeneration, immune modulation, and hepatic health. It serves as a precursor for the synthesis of genetic material (DNA/RNA) and ATP, making it an essential ingredient in functional foods, infant formulas, and premium anti-aging cosmetics.

Category:
Keywords:
sodium
ribonucleic
Functions
1.Immune System Enhancement
Sodium RNA provides exogenous nucleotides that rapidly proliferating cells (like immune cells and intestinal epithelial cells) require but cannot synthesize efficiently de novo during stress. Supplementation boosts lymphocyte proliferation and macrophage activity.
2.Cellular Repair & Regeneration
It supports the repair of damaged tissues, particularly in the liver and gut. By facilitating protein synthesis and cell division, it accelerates recovery from injury or surgery.
3.Flavor Enhancement (Umami)
Enzymatic hydrolysis of RNA yields 5'-Nucleotides (GMP and IMP), which are potent flavor enhancers (Umami). While Sodium RNA itself is the polymeric precursor, it is often the starting material for natural savory flavor production.

Applications
• Functional Foods & Infant Formula: Added to milk powders and recovery shakes to mimic the nucleotide profile of breast milk and support infant immune development.
• Pharmaceuticals: Used as an adjuvant therapy for chronic hepatitis, leukopenia, and to mitigate the side effects of chemotherapy.
• Cosmetics: Incorporated into anti-aging creams for its ability to promote skin cell turnover and repair UV-induced DNA damage.
• Animal Nutrition: High-grade feed additive for young animals (piglets, aquaculture) to improve growth performance and disease resistance.

Flow Chart
Our sustainable yeast-based process ensures product safety and consistency:
1.Fermentation: Cultivation of non-GMO Saccharomyces cerevisiae in nutrient-rich media.
2.Cell Lysis: Mechanical or enzymatic breaking of yeast cell walls.
3.Extraction: Solubilization of intracellular RNA using salt solutions.
4.Separation: Centrifugation to remove cell debris and proteins.
5.Precipitation: Controlled precipitation of RNA using ethanol or acid.
6.Neutralization: Forming the Sodium salt for improved solubility.
7.Drying: Spray drying to produce the final powder.

Quality Standard of Lactoferrin
Product: Sodium Ribonucleic Acid (Food/Pharma Grade)
CAS No.: 9009-85-2
| Item | Specification | Result |
| Appearance | Yellow to yellowish-brown powder | Conforms |
| Assay (on dry basis) | ≥ 85.0% | 91.5% |
| Moisture | ≤9.0% | 7.4% |
| pH (1% Solution) | 2.8-3.8 | 3.2 |
| Solubility | Soluble in water, insoluble in ethanol | Conforms |
| Heavy Metals (Pb) | ≤10 ppm | < 10 ppm |
| Arsenic (As) | ≤2 ppm | < 1 ppm |
| Total Plate Count | ≤ 10000 CFU/g | Conforms |
| Yeast & Mold | ≤ 1000 CFU/g | Conforms |
Method of Analysis of Lactoferrin
• Assay: Determined via UV-Vis Spectrophotometry at 260 nm (using extinction coefficient) or by Phosphorus Determination.
• Purity Verification: The ratio of Absorbance at 250nm/260nm and 280nm/260nm is measured to ensure the RNA is free from significant protein or phenol contamination.
Reference Chromatogram of Lactoferrin Reference Substance
While typically analyzed via UV, HPLC analysis of the hydrolyzed product shows distinct peaks for the constituent nucleotides (AMP, GMP, CMP, UMP), confirming the integrity of the RNA source. Impurity peaks related to DNA or Protein are minimal.

Stability and Safety
Stability Studies
• Shelf Life: 24 months.
• Hygroscopicity: Sodium RNA is hygroscopic.
• Stability Data: Samples stored in aluminum foil bags at 25°C/60% RH showed <2% degradation in assay over 18 months. High humidity causes caking and potential degradation.
Safety & Handling (MSDS Summary)
• Classification: Non-hazardous food ingredient (GRAS in many applications).
• Handling: Wear a dust mask to prevent inhalation of fine powder.
• Storage: Store in a cool, dry place. Keep container tightly sealed. Avoid moisture and direct sunlight.
Customer Comments
Technical Director, Flavor House, Germany
2026.04.02
★★★★☆
Animal Nutritionist, Feed Co., Thailand
2026.04.02
★★★★☆
Our Certificates
Our Clients
Exhibitions
Meet Manager and our technical team at:
• Hi Europe (Health Ingredients)
• FIC China (Shanghai)
• SupplySide West (Las Vegas)
FIC2024
CPHI & PMEC China 2025
CAC 24th
CAC Shanghai
CPHI & PMEC 2024
CPHI & PMEC China Shanghai
CPHI 2025
CPHI 2024
CPHI 2023
FIC 2022
FIC 2023
FIC Shanghai
CPHI Korea
SupplySideWEST Las Vegas
SupplySideWEST 2023
Vitafoods Europe Switzerland
Wagri Guangzhou
In-Cosmetics Global
SupplySide West (Las Vegas)
SupplySide West (Las Vegas)
Vitafoods Europe (Geneva)
CPhI Worldwide
FAQ
What is the source of your Sodium RNA?
It is extracted solely from Baker's Yeast (Saccharomyces cerevisiae) or Torula Yeast. We do not use animal organs, ensuring it is suitable for Vegetarian, Halal, and Kosher diets.
Is this product soluble in water?
Yes, as the sodium salt form, it is fully soluble in water, making it easy to incorporate into beverages, liquid medicines, and cosmetic lotions.
Can it be used in cosmetics?
Absolutely. Sodium RNA is a popular anti-aging ingredient. It conditions the skin and supports the natural repair processes. It is often listed as "Hydrolyzed RNA" or "Sodium RNA" on INCI lists.
References
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