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Sodium Ribonucleic Acid

Sodium Ribonucleic Acid Manufacturer | Immune Booster & Cellular Repair (CAS: 9009-85-2) Source: Saccharomyces cerevisiae (Yeast) | Purity: 85.0% (Enzymatic Method) | Certifications: ISO9001, HACCP, Halal, Kosher High Nucleotide Content | Non-GMO Yeast Origin | Ready Stock in Local Warehouse

Introduction


Sodium Ribonucleic Acid (Sodium RNA; CAS: 9009-85-2) is a biologically active macromolecule extracted from high-quality food-grade yeast (Saccharomyces cerevisiae). Through controlled fermentation and advanced separation technologies, we obtain a high-purity sodium salt form of RNA that is water-soluble and highly bioavailable.

As a rich source of dietary nucleotides, Sodium RNA plays a pivotal role in cellular regeneration, immune modulation, and hepatic health. It serves as a precursor for the synthesis of genetic material (DNA/RNA) and ATP, making it an essential ingredient in functional foods, infant formulas, and premium anti-aging cosmetics.

Category:

Keywords:

sodium

ribonucleic

Functions


1.Immune System Enhancement

Sodium RNA provides exogenous nucleotides that rapidly proliferating cells (like immune cells and intestinal epithelial cells) require but cannot synthesize efficiently de novo during stress. Supplementation boosts lymphocyte proliferation and macrophage activity.

2.Cellular Repair & Regeneration

It supports the repair of damaged tissues, particularly in the liver and gut. By facilitating protein synthesis and cell division, it accelerates recovery from injury or surgery.

3.Flavor Enhancement (Umami)

Enzymatic hydrolysis of RNA yields 5'-Nucleotides (GMP and IMP), which are potent flavor enhancers (Umami). While Sodium RNA itself is the polymeric precursor, it is often the starting material for natural savory flavor production.

Applications


• Functional Foods & Infant Formula: Added to milk powders and recovery shakes to mimic the nucleotide profile of breast milk and support infant immune development.

• Pharmaceuticals: Used as an adjuvant therapy for chronic hepatitis, leukopenia, and to mitigate the side effects of chemotherapy.

• Cosmetics: Incorporated into anti-aging creams for its ability to promote skin cell turnover and repair UV-induced DNA damage.

• Animal Nutrition: High-grade feed additive for young animals (piglets, aquaculture) to improve growth performance and disease resistance.

Flow Chart


Our sustainable yeast-based process ensures product safety and consistency:

1.Fermentation: Cultivation of non-GMO Saccharomyces cerevisiae in nutrient-rich media.

2.Cell Lysis: Mechanical or enzymatic breaking of yeast cell walls.

3.Extraction: Solubilization of intracellular RNA using salt solutions.

4.Separation: Centrifugation to remove cell debris and proteins.

5.Precipitation: Controlled precipitation of RNA using ethanol or acid.

6.Neutralization: Forming the Sodium salt for improved solubility.

7.Drying: Spray drying to produce the final powder.

Quality Standard of Lactoferrin


Product: Sodium Ribonucleic Acid (Food/Pharma Grade)

CAS No.: 9009-85-2

ItemSpecificationResult
AppearanceYellow to yellowish-brown powderConforms
Assay (on dry basis)≥ 85.0%91.5%
Moisture≤9.0%7.4%
pH (1% Solution)2.8-3.83.2
SolubilitySoluble in water, insoluble in ethanolConforms
Heavy Metals (Pb)≤10 ppm< 10 ppm
Arsenic (As)≤2 ppm< 1 ppm
Total Plate Count≤ 10000 CFU/gConforms
Yeast & Mold≤ 1000 CFU/gConforms

Method of Analysis of Lactoferrin


• Assay: Determined via UV-Vis Spectrophotometry at 260 nm (using extinction coefficient) or by Phosphorus Determination.

• Purity Verification: The ratio of Absorbance at 250nm/260nm and 280nm/260nm is measured to ensure the RNA is free from significant protein or phenol contamination.

Reference Chromatogram of Lactoferrin Reference Substance


While typically analyzed via UV, HPLC analysis of the hydrolyzed product shows distinct peaks for the constituent nucleotides (AMP, GMP, CMP, UMP), confirming the integrity of the RNA source. Impurity peaks related to DNA or Protein are minimal.

Stability and Safety


Stability Studies

• Shelf Life: 24 months.

• Hygroscopicity: Sodium RNA is hygroscopic.

• Stability Data: Samples stored in aluminum foil bags at 25°C/60% RH showed <2% degradation in assay over 18 months. High humidity causes caking and potential degradation.

Safety & Handling (MSDS Summary)

• Classification: Non-hazardous food ingredient (GRAS in many applications).

• Handling: Wear a dust mask to prevent inhalation of fine powder.

• Storage: Store in a cool, dry place. Keep container tightly sealed. Avoid moisture and direct sunlight.

Long-term stability testing of Ribonucleic acid

MSDS-Ribonucleic acid

Customer Comments


Technical Director, Flavor House, Germany

Technical Director, Flavor House, Germany

2026.04.02

★★★★☆

"We use your Sodium RNA as the substrate for our nucleotide production. The yield is consistently high, and the heavy metal profile meets our strict EU standards."
Animal Nutritionist, Feed Co., Thailand

Animal Nutritionist, Feed Co., Thailand

2026.04.02

★★★★☆

"Added this to our piglet creep feed. We noticed a significant reduction in diarrhea and better weight gain during weaning."

Our Certificates


CERTIFICATE

CERTIFICATE

CERTIFICATE

CERTIFICATE

FDA

FDA

ISO

ISO

HALAL

HALAL

HACCP

HACCP

Our Clients


Abbott
Big Bear Pharmaceuticals
Spring season
HIEIDO
Oil and Fat Corporation
Dalian University
China Pharmaceutical University
Shenyang Pharmaceutical University
SIOC
SIMM
KANS
Renhe Pharmaceutical
JNJ
HANHOO
Korea University
Kyeonggi University
LG
Samyang Foods
AJINOMOTO
PipingRock‌
DSM-Firmenich
Beijing Tongrentang
Nestlé
BIOHIGH
Evonik Industries
Herbalife Nutrition
L'ORÉAL
STARFIELD
Unilever
MERCK

Exhibitions


Meet Manager and our technical team at:

• Hi Europe (Health Ingredients)

• FIC China (Shanghai)

• SupplySide West (Las Vegas)

FIC2024

FIC2024

CPHI & PMEC China 2025

CPHI & PMEC China 2025

CAC 24th

CAC 24th

CAC Shanghai

CAC Shanghai

CPHI & PMEC 2024

CPHI & PMEC 2024

CPHI & PMEC China Shanghai

CPHI & PMEC China Shanghai

CPHI 2025

CPHI 2025

CPHI 2024

CPHI 2024

CPHI 2023

CPHI 2023

FIC 2022

FIC 2022

FIC 2023

FIC 2023

FIC Shanghai

FIC Shanghai

CPHI Korea

CPHI Korea

SupplySideWEST Las Vegas

SupplySideWEST Las Vegas

SupplySideWEST 2023

SupplySideWEST 2023

Vitafoods Europe Switzerland

Vitafoods Europe Switzerland

Wagri Guangzhou

Wagri Guangzhou

In-Cosmetics Global

In-Cosmetics Global

SupplySide West (Las Vegas)

SupplySide West (Las Vegas)

SupplySide West (Las Vegas)

SupplySide West (Las Vegas)

Vitafoods Europe (Geneva)

Vitafoods Europe (Geneva)

CPhI Worldwide

CPhI Worldwide

FAQ


What is the source of your Sodium RNA?

It is extracted solely from Baker's Yeast (Saccharomyces cerevisiae) or Torula Yeast. We do not use animal organs, ensuring it is suitable for Vegetarian, Halal, and Kosher diets.

Is this product soluble in water?

Yes, as the sodium salt form, it is fully soluble in water, making it easy to incorporate into beverages, liquid medicines, and cosmetic lotions.

Can it be used in cosmetics?

Absolutely. Sodium RNA is a popular anti-aging ingredient. It conditions the skin and supports the natural repair processes. It is often listed as "Hydrolyzed RNA" or "Sodium RNA" on INCI lists.

References


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