Phlorotannin Powder
Phlorotannin Powder Manufacturer | Marine Polyphenol & Antioxidant (CAS: N/A) Source: Ecklonia cava / Brown Algae | Purity: 95% (UV) | Certifications: ISO9001, Kosher, Halal USP: Stronger Antioxidant than Green Tea | Long Half-Life (12+ Hours) | Sleep & Memory Support
Introduction
Phlorotannin Powder is a concentrated extract of unique marine polyphenols derived primarily from edible brown algae (Phaeophyceae) such as Ecklonia cava. Unlike land-based polyphenols (like catechins or resveratrol) which are comprised of 3-4 phenol rings, Phlorotannins are polymers of phloroglucinol units (1,3,5-trihydroxybenzene), forming a robust molecular structure with up to 8 interconnected phenol rings.
This unique structure grants Phlorotannins superior stability and a significantly longer half-life in the human body (up to 12 hours) compared to terrestrial antioxidants (~30 minutes), making them highly effective for sustained free radical scavenging.
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phlorotannin
powder
Functions
1.Super Antioxidant Power
Phlorotannins exhibit an Oxygen Radical Absorbance Capacity (ORAC) value significantly higher than that of Vitamin C and Green Tea catechins. They effectively neutralize reactive oxygen species (ROS), protecting cells from oxidative stress and DNA damage.
2.Sleep Quality Improvement
Research indicates that specific phlorotannins (like Dieckol) can modulate the GABA$_A$-benzodiazepine receptor complex, promoting relaxation and reducing sleep latency without the side effects of pharmaceutical sedatives.
3.Weight Management & Metabolic Health
They inhibit pancreatic lipase activity, reducing the absorption of dietary fats. Additionally, they activate AMPK pathways, helping to regulate blood glucose levels and improve insulin sensitivity.
Applications
• Dietary Supplements: "Marine Polyphenol" capsules for anti-aging, sleep support, and metabolic syndrome management.
• Functional Foods: Added to beverages and health bars for sustained antioxidant protection.
• Cosmetics: A powerful ingredient in anti-aging creams to inhibit matrix metalloproteinases (MMPs), reducing wrinkle formation and protecting against UV photo-aging.
• Aquaculture Feed: Used as a natural additive to boost immunity and disease resistance in farmed fish and shrimp.
Flow Chart
Our solvent-free extraction process ensures high purity and bioactivity:
1.Harvesting: Sustainable collection of wild Ecklonia cava or Laminaria species.
2.Washing & Desalination: Removing salt and surface impurities.
3.Extraction: Hot water or Ethanol/Water extraction (Controlled temperature < 60°C).
4.Filtration: Removing algal biomass.
5.Purification: Column chromatography to concentrate the Phlorotannin fraction and remove heavy metals/iodine.
6.Concentration: Vacuum evaporation.
7.Spray Drying: Producing a fine, water-soluble powder.
Quality Standard of Lactoferrin
Product: Phlorotannin Powder (Standardized Extract) Source: Brown Algae (Ecklonia cava)
| Item | Specification | Result |
| Appearance | Light brown to tan powder | Conforms |
| Total Phlorotannins (UV) | 95.0% | 95.8% |
| Dieckol Content (HPLC) | 5.0% (Customizable) | 6.2% |
| Loss on Drying | 5.0% | 3.5% |
| Ash Content | 5.0% | 2.1% |
| Heavy Metals (Pb) | 3 ppm | < 1 ppm |
| Arsenic (As) | 1 ppm | < 0.5 ppm |
| Iodine | < 100 ppm (Controlled) | 45 ppm |
| Solubility | Soluble in water | Conforms |
Method of Analysis of Lactoferrin
• Total Polyphenols: Measured via the Folin-Ciocalteu method, using Phloroglucinol as a standard equivalent.
• HPLC Fingerprint: Used to identify specific bioactive markers such as Dieckol, Eckol, and 6,6'-Bieckol, ensuring the authenticity of the marine source.
Reference Chromatogram of Lactoferrin Reference Substance
The HPLC profile displays characteristic peaks for the major phlorotannin oligomers. Unlike generic seaweed extracts, our chromatogram confirms the high concentration of bioactive dimers and trimers (Dieckol/Eckol) essential for functional efficacy.
Stability and Safety
Stability Studies
• Shelf Life: 24 months.
• Heat Stability: Phlorotannins are remarkably heat-stable compared to green tea catechins, retaining antioxidant activity even after pasteurization temperatures.
• Data: Samples stored at 25°C/60% RH showed <3% loss in total polyphenol content over 2 years.
Safety & Handling (MSDS Summary)
• Classification: Non-hazardous natural extract.
• Iodine Caution: While purified, individuals with thyroid conditions should consult a physician. Our process minimizes iodine content.
• Storage: Store in a cool, dry place. Hygroscopic; keep container tightly sealed.
Customer Comments
Product Developer, US Nutraceutical Brand
2026.04.02
★★★★☆
R&D Manager, Beverage Co., South Korea
2026.04.02
★★★★☆
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FAQ
How is Phlorotannin different from other polyphenols?
Structurally, it is a polymer of phloroglucinol (found only in brown algae), whereas land plant polyphenols are based on gallic acid or flavones. This gives Phlorotannins a unique "trapping" ability for free radicals and a blood circulation half-life of 12 hours vs. 30 mins for catechins.
Does it contain high levels of Iodine?
Raw brown algae is high in iodine, but our Phlorotannin Powder undergoes a specific purification process to reduce iodine to safe trace levels (<100 ppm), making it suitable for daily supplementation without thyroid risks.
What is the recommended dosage?
For general antioxidant support: 100-300 mg/day. For sleep support or metabolic benefits, clinical studies often use dosages ranging from 250-500 mg/day.
References
1.Li, Y., et al. (2011). "Health benefits of phlorotannins from brown seaweeds." Journal of Applied Phycology.
2.Yoon, N.Y., et al. (2009). "Phlorotannins from Ecklonia cava inhibit matrix metalloproteinases..." Journal of Agricultural and Food Chemistry.
3.Heo, S.J., et al. (2009). "Protective effect of phlorotannins from Ecklonia cava on murine memory deficit." British Journal of Pharmacology.
4.Kang, S.M., et al. (2012). "Molecular docking studies of phlorotannins... as inhibitors of alpha-glucosidase." Bioorganic & Medicinal Chemistry.
5.Shibata, T., et al. (2004). "Inhibitory activity of brown algal phlorotannins against hyaluronidase." International Journal of Food Science & Technology.
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