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Phosphatidylserine

Phosphatidylserine (PS) Powder | Brain Health Ingredient Headline: High-Purity Phosphatidylserine (PS) Manufacturer | 20% - 90% Powder (CAS: 51446-62-9) Sub-info: Source: Non-GMO Soybean / Sunflower | Assay: 20%, 50%, 70%~90%| Shelf Life: 24 Months USP: The "Brain Gold" Nutrient • Soy-Free Options Available • Cortisol Management

Introduction


P&K

Phosphatidylserine (PS) is a phospholipid nutrient derived from natural soybean lecithin or sunflower seeds via advanced enzymatic hydrolysis. Dubbed "Brain Gold" in industry circles, it is the only phospholipid that can regulate the functional status of key proteins in cell membranes.

As a critical component of neural cell membranes, PS is capable of crossing the blood-brain barrier to directly nourish brain cells. To cater to diverse formulation requirements across the global market, we offer two variants: Soy-Derived PS (Classic Version) and Sunflower-Derived PS (Allergen-Free Version).

Category:

Keywords:

phosphatidylserine

sunflower

allergen-free

Functions


1.Cognitive Enhancement (Memory & Focus)

PS plays a vital role in maintaining cellular fluidity within the brain. It promotes the release of neurotransmitters (such as Acetylcholine and Dopamine) and facilitates synaptic transmission. Clinical trials have demonstrated that a daily intake of 300mg can enhance memory recall and concentration in both student populations and the elderly.

2.Stress Relief & Cortisol Regulation

By mitigating the release of cortisol (the primary stress hormone) triggered by physical or mental stress, PS helps alleviate fatigue and reduce anxiety. This makes it a sought-after ingredient in stress-relief supplements and sports recovery formulations.

3.Supporting Children with ADHD

Research suggests that PS supplementation can improve attention span and reduce behavioral symptoms in children with ADHD by stabilizing neural activity in the prefrontal cortex.

Applications


Dietary Supplements

• Brain Health Tablets: Frequently combined with DHA, Ginkgo Biloba, or Bacopa to deliver comprehensive cognitive support.

• Sleep Aids: Works synergistically with Melatonin or Magnesium to address sleep issues associated with cortisol imbalance.

Functional Foods

• Infant Formula: Fortified with PS to support early-stage brain development.

• Smart Beverages: Water-dispersible grades are available for use in energy drinks and focus-enhancing beverages.

Sports Nutrition

• Recovery Powders: Helps reduce muscle soreness and mitigate exercise-induced stress.

Flow Chart


Note: Our enzymatic transphosphatidylation process ensures high specificity and avoids the use of harsh chemical solvents.

Quality Standard of Lactoferrin


Testing itemTesting standardResult
Assay≥70%71.5%
AppearanceLight yellow to brown yellowish powderConforms
IdentificationCharacteristic odorConforms
Water≤2.0%0.54%
Peroxide Value≤5.0meq/kg2.0meq/kg
Heavy Metals≤10ppmConforms
Arsenic≤1ppmConforms
Lead≤3ppmConforms
Cadmium≤1ppmConforms
Mercury≤0. 1ppmConforms
Total Plate Count≤1000CFU/g100CFU/g
Yeast & Mold≤100CFU/g<10CFU/g
Coliform<3.0MNP/gConforms
E.ColiNegativeNegative
SalmonellaNegativeNegative
StaphylococcusNegativeNegative
ConclusionThis product testing according to<Enterprise Standard>

Method of Analysis of Lactoferrin


We use HPLC-ELSD for the most accurate quantification.

Reference Chromatogram of Lactoferrin Reference Substance


Stability and Safety


Stability Studies

• Shelf Life: 12 months.

• Oxidation: PS is a lipid substance and prone to oxidation.

• Storage: Store in a cool, dry place. Avoid high light temperature and strong light.

Safety & Handling (MSDS Summary)

• Classification: GRAS (Generally Recognized As Safe) by US FDA.

• Allergen Info:

 ◯ Soy PS: Contains Soy.

 ◯ Sunflower PS: Allergen-Free.

• Handling: Wear standard PPE.

long-term stability testing of Phosphatidylserine

MSDS of Phosphatidylserine

Customer Comments


Product Developer, Australian Infant Nutrition Co.

Product Developer, Australian Infant Nutrition Co.

2026.03.03

★★★★☆

"Your Sunflower PS 50% was a game changer for our allergen-free kids' line. The powder flow is great for our stick packs."
Quality Manager, US Softgel Manufacturer

Quality Manager, US Softgel Manufacturer

2026.03.03

★★★★☆

"We tested the peroxide value upon arrival, and it was very low (<3 meq/kg). This freshness is crucial for us."

Our Certificates


CERTIFICATE

CERTIFICATE

CERTIFICATE

CERTIFICATE

FDA

FDA

ISO

ISO

HALAL

HALAL

HACCP

HACCP

Our Clients


Abbott
Big Bear Pharmaceuticals
Spring season
HIEIDO
Oil and Fat Corporation
Dalian University
China Pharmaceutical University
Shenyang Pharmaceutical University
SIOC
SIMM
KANS
Renhe Pharmaceutical
JNJ
HANHOO
Korea University
Kyeonggi University
LG
Samyang Foods
AJINOMOTO
PipingRock‌
DSM-Firmenich
Beijing Tongrentang
Nestlé
BIOHIGH
Evonik Industries
Herbalife Nutrition
L'ORÉAL
STARFIELD
Unilever
MERCK

Exhibitions


• Vitafoods Europe (Geneva)

• SupplySide West (Las Vegas)

• Hi Japan (Tokyo)

Vitafoods Europe (Geneva)

Vitafoods Europe (Geneva)

CPhI Worldwide

CPhI Worldwide

CPHI & PMEC China 2025

CPHI & PMEC China 2025

CAC 24th

CAC 24th

CAC Shanghai

CAC Shanghai

CPHI & PMEC 2024

CPHI & PMEC 2024

CPHI & PMEC China Shanghai

CPHI & PMEC China Shanghai

CPHI 2025

CPHI 2025

CPHI 2024

CPHI 2024

CPHI 2023

CPHI 2023

FIC 2022

FIC 2022

FIC 2023

FIC 2023

FIC Shanghai

FIC Shanghai

FIC2024

FIC2024

CPHI Korea

CPHI Korea

SupplySideWEST Las Vegas

SupplySideWEST Las Vegas

SupplySideWEST 2023

SupplySideWEST 2023

Vitafoods Europe Switzerland

Vitafoods Europe Switzerland

Wagri Guangzhou

Wagri Guangzhou

In-Cosmetics Global

In-Cosmetics Global

SupplySide West (Las Vegas)

SupplySide West (Las Vegas)

SupplySide West (Las Vegas)

SupplySide West (Las Vegas)

FAQ


Why choose Sunflower PS over Soybean PS?

Soybean PS is the traditional, cost-effective choice. However, Sunflower PS is 100% Non-GMO and Allergen-Free (No Soy). It is ideal for "Clean Label" products and consumers with soy allergies.

What is the recommended dosage?

Clinical studies typically use 100mg to 300mg of pure PS per day. For a 50% powder, this means formulating 200mg-600mg of raw material.

Can it be used in gummies?

Yes. However, phospholipids can affect texture. We recommend adding it at the end of the cooking process to avoid high heat exposure (which can degrade the lipids) and using masking flavors if using high dosages.

References


1.Glade, M. J., & Smith, K. "Phosphatidylserine and the human brain." Nutrition (2015).

2.Crook, T. H., et al. "Effects of phosphatidylserine in age-associated memory impairment." Neurology (1991).

3.Hirayama, S., et al. "The effect of phosphatidylserine administration on memory and symptoms of attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled clinical trial." Journal of Human Nutrition and Dietetics (2014).

4.Monteleone, P., et al. "Effects of phosphatidylserine on the neuroendocrine response to physical stress in humans." Neuroendocrinology (1990).

5.Kato-Kataoka, A., et al. "Soybean-derived phosphatidylserine improves memory function of the elderly Japanese subjects with memory complaints." Journal of Clinical Biochemistry and Nutrition (2010).

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