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Chitin

Chitin Powder Manufacturer | High Purity Biopolymer (CAS: 1398-61-4) Headline: Premium Chitin Manufacturer | High Purity Biopolymer for Pharma & Agriculture (CAS: 1398-61-4) Sub-headline: Sourced from Deep-Sea Crustaceans | Consistent Acetylation Degree | FDA/GRAS Compliant Facility Unique Selling Proposition (USP): • High Purity Source: Extracted from premium snow crab/shrimp shells with low heavy metal content. • Controlled Parameters: Strict control on Ash (<1%) and Protein (<1%) for pharmaceutical grade applications. • Versatile Raw Material: The essential precursor for Glucosamine and Chitosan production.

Introduction


P&K

Chitin (CAS: 1398-61-4) is the second most abundant natural biopolymer in the world, after cellulose. Chemically known as poly-β-(1→4)-N-acetyl-D-glucosamine, it is the primary structural component of the exoskeletons of crustaceans (crabs, shrimp) and fungal cell walls.

Unlike Chitosan, Chitin retains its acetyl groups, making it highly stable and insoluble in water and most organic solvents. Our Chitin is processed using a mild demineralization and deproteinization method to preserve its high molecular weight and biological integrity, serving as a critical raw material for the nutraceutical, pharmaceutical, and agricultural industries.

Category:

Keywords:

chitin

chitosan

biopolymer

Functions


1.Biomedical & Wound Healing

• Mechanism: Chitin fibers possess unique structural properties that mimic the Extracellular Matrix (ECM).

• Action: Accelerates wound healing by promoting macrophage activation and fibroblast proliferation. Often used in artificial skin matrices and absorbable sutures.

2.Agricultural Elicitor

• Mechanism: Acts as a Pathogen-Associated Molecular Pattern (PAMP) in plants.

• Action: Triggers the plant's natural immune defense system, boosting resistance against fungal and bacterial infections (e.g., Fusarium, Botrytis) without using toxic pesticides.

3.Precursor Synthesis

• Mechanism: Hydrolysis and Deacetylation.

• Action: It is the starting material for producing Glucosamine (joint health) and Chitosan (water treatment, weight loss), determining the quality of the final derivative.

Applications


1.Pharmaceutical & Medical Devices

• Application: Wound dressings, surgical sutures, and drug delivery carriers.

• Why it works: Its biocompatibility and biodegradability prevent immune rejection while facilitating tissue regeneration.

2.Agriculture & Feed

• Application: Soil amendments and seed coatings.

• Why it works: Enhances root development and stimulates the growth of beneficial soil microorganisms (chitinolytic bacteria), improving crop yield.

3.Industrial & Cosmetic

• Application: Thickening agents and textile finishing.

• Why it works: Provides structural integrity and moisture retention in formulations.

Flow Chart


1.Raw Material Preparation: Washing and crushing of fresh shrimp/crab shells.

2.Demineralization: Acid treatment (HCl) to remove Calcium Carbonate.

3.Deproteinization: Alkali treatment (NaOH) to remove proteins.

4.Decolorization: Mild oxidation to remove pigments (Astaxanthin).

5.Washing & Neutralization: Multiple wash cycles to reach pH 7.

6.Drying: Hot air drying to moisture <10%.

7.Milling & Sieving: Grinding to specified mesh size (e.g., 80 mesh).

8.Packaging: 25kg Drum/Bag with liners.

(Note: Environmental controls include acid/alkali recovery systems to minimize waste)

Quality Standard of Lactoferrin


Product: Chitin (Pharmaceutical Grade)

Source: Snow Crab Shell

ItemSpecificationResult
AppearanceWhite to off-white powder/flakesConforms
Assay (N-Acetyl-D-glucosamine)≥ 90.0%92.5%
Ash Content≤ 1.0%0.6%
Protein Content≤ 1.0%0.3%
Moisture (Loss on Drying)≤ 10.0%7.8%
Heavy Metals (Pb)≤ 10 ppm< 5 ppm
Arsenic (As)≤ 1 ppm< 0.5 ppm
MicrobiologyTotal Plate Count < 1000 cfu/gConforms

Method of Analysis of Lactoferrin


Test Method: Elemental Analysis / Acid-Base Titration

• Procedure for Purity: The degree of acetylation (DA) is often measured via FT-IR Spectroscopy or H-NMR, comparing the ratio of acetylated units to free amino units.

• Ash Testing: Calcination at 600°C ensures thorough demineralization (removal of Calcium Carbonate).

Reference Chromatogram of Lactoferrin Reference Substance


For Chitin, FT-IR (Fourier Transform Infrared Spectroscopy) is the standard identification method.

• Key Peaks: A high-quality Chitin spectrum shows characteristic amide bands: Amide I (approx. 1650 cm⁻¹) and Amide II (approx. 1550 cm⁻¹), indicating the integrity of the N-acetyl groups. Absence of calcium carbonate peaks (876 cm⁻¹) confirms successful demineralization.

Stability and Safety


Stability Studies

• Long-term Stability (24 Months): Samples stored at Room Temperature (25°C) in sealed containers showed no degradation in polymer chain length or color change.

• Moisture Sensitivity: Chitin is hygroscopic. Tests at high humidity (75% RH) indicate moisture uptake; therefore, proper sealing is critical.

• Conclusion: Supports a 3-year shelf life if kept dry.

Safety & Handling (MSDS Summary)

• Classification: Non-hazardous natural polymer. GRAS (Generally Recognized As Safe) for certain applications.

• Handling: Nuisance dust. Use local exhaust ventilation.

• Allergen Warning: Contains Crustacean Shell Derivatives. Must be labeled for shellfish allergies.

• Storage: Store in a cool, dry area. Avoid moisture.

long-term stability testing of Chitin

msds of chitin

Customer Comments


Production Manager, JointCare Pharma (Germany)

Production Manager, JointCare Pharma (Germany)

2026.03.03

★★★★☆

"We use this Chitin for our Glucosamine production. The low ash content saves us significant processing time in the hydrolysis step."
R&D Director, GreenCrop Solutions (USA)

R&D Director, GreenCrop Solutions (USA)

2026.03.03

★★★★☆

"The consistency of the particle size is perfect for our agricultural soil amendment blends. It mixes evenly without clumping."

Our Certificates


CERTIFICATE

CERTIFICATE

CERTIFICATE

CERTIFICATE

FDA

FDA

ISO

ISO

HALAL

HALAL

HACCP

HACCP

Our Clients


Abbott
Big Bear Pharmaceuticals
Spring season
HIEIDO
Oil and Fat Corporation
Dalian University
China Pharmaceutical University
Shenyang Pharmaceutical University
SIOC
SIMM
KANS
Renhe Pharmaceutical
JNJ
HANHOO
Korea University
Kyeonggi University
LG
Samyang Foods
AJINOMOTO
PipingRock‌
DSM-Firmenich
Beijing Tongrentang
Nestlé
BIOHIGH
Evonik Industries
Herbalife Nutrition
L'ORÉAL
STARFIELD
Unilever
MERCK

Exhibitions


• Vitafoods Europe (Geneva)

• CPhI Worldwide

• AgriBusiness Global Trade Summit

FIC Shanghai

FIC Shanghai

FIC2024

FIC2024

CPHI Korea

CPHI Korea

SupplySideWEST Las Vegas

SupplySideWEST Las Vegas

SupplySideWEST 2023

SupplySideWEST 2023

Vitafoods Europe Switzerland

Vitafoods Europe Switzerland

Wagri Guangzhou

Wagri Guangzhou

In-Cosmetics Global

In-Cosmetics Global

SupplySide West (Las Vegas)

SupplySide West (Las Vegas)

SupplySide West (Las Vegas)

SupplySide West (Las Vegas)

CPHI & PMEC China 2025

CPHI & PMEC China 2025

CAC 24th

CAC 24th

CAC Shanghai

CAC Shanghai

CPHI & PMEC 2024

CPHI & PMEC 2024

CPHI & PMEC China Shanghai

CPHI & PMEC China Shanghai

CPHI 2025

CPHI 2025

CPHI 2024

CPHI 2024

CPHI 2023

CPHI 2023

FIC 2022

FIC 2022

FIC 2023

FIC 2023

Vitafoods Europe (Geneva)

Vitafoods Europe (Geneva)

CPhI Worldwide

CPhI Worldwide

FAQ


What is the difference between Chitin and Chitosan?

Chitin is the native polymer with acetyl groups (insoluble). Chitosan is the deacetylated derivative (soluble in weak acids). Chitin is used when physical stability and structural strength are required, or as a raw material.

Is your Chitin vegan?

No, our standard Chitin is sourced from crustacean shells (crab/shrimp). However, we can offer Fungal Chitin (Aspergillus niger origin) upon special request for vegan applications.

What mesh sizes are available?

We offer flakes (for extraction) and fine powders (80 mesh, 100 mesh) for direct formulation or agricultural spraying.

References


1.Rinaudo, M. (2006). "Chitin and chitosan: Properties and applications." Progress in Polymer Science.

2.Pillai, C.K.S., et al. (2009). "Chitin and chitosan polymers: Chemistry, solubility and fiber formation."

3.Hamid, R., et al. (2010). "Chitin and Chitosan Derivatives as Biomaterial." Journal of Materials Science: Materials in Medicine.

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