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Chitosan

Chitosan Powder | High-Purity Biopolymer Manufacturer Headline: Premium Chitosan Powder Manufacturer | High Deacetylation Degree (CAS: 9012-76-4) Sub-info: Source: Snow Crab / Shrimp Shells | Deacetylation: 85% - 95% | Viscosity: Customizable (20-1000 cps) USP: High Density Grade • Heavy Metal Controlled (<10ppm) • Biodegradable & Non-Toxic

Introduction


P&K

Chitosan is a linear polysaccharide composed of randomly distributed β-(1-4)-linked D-glucosamine and N-acetyl-D-glucosamine. It is produced by the deacetylation of Chitin, the structural element in the exoskeleton of crustaceans.

Our Chitosan is distinguished by its high degree of deacetylation (D.D. >90%), which directly correlates to its biological activity and solubility. We offer specific molecular weight and viscosity grades tailored for dietary supplements, agriculture, and cosmetic formulations.

Category:

Keywords:

chitosan

deacetylation

manufacturer

Functions


1.Weight Management (Fat Binding)

Chitosan carries a strong positive ionic charge. In the stomach, it binds to negatively charged dietary fats and bile acids, forming an indigestible gel that prevents fat absorption. This "fat magnet" effect makes it a popular ingredient in weight loss supplements.

2.Agricultural Biostimulant

In agriculture, Chitosan triggers plant defense mechanisms (systemic acquired resistance), boosting immunity against fungal infections. It also stimulates root growth and improves crop yield, serving as a natural, eco-friendly alternative to chemical pesticides.

3.Wound Healing & Hemostasis

Chitosan possesses intrinsic antimicrobial and hemostatic properties. It promotes blood clotting and accelerates tissue regeneration, making it an essential material for medical dressings, bandages, and surgical gels.

Applications


Nutraceuticals:

• Fat Blockers: Capsules taken before meals to reduce calorie absorption.

• Cholesterol Support: Helps lower LDL cholesterol levels.

Agriculture:

• Seed Coating: Protects seeds from pathogens and enhances germination.

• Foliar Spray: Elicits natural defense responses in crops.

Water Treatment:

• Flocculant: A natural chelating agent used to remove heavy metals and suspended solids from wastewater.

Flow Chart


Raw Material (Crab/Shrimp Shells) → Washing & Crushing → Deproteinization (Alkaline Treatment) → Demineralization (Acid Treatment) → Chitin → Deacetylation (High Conc. NaOH) → Washing (Neutralization) → Drying → Milling → Quality Control (Viscosity/D.D.) → Packaging

Note: We use a controlled temperature deacetylation process to ensure a uniform distribution of amino groups without degrading the polymer chain length.

Quality Standard of Lactoferrin


ItemSpecification (Food/Pharma Grade)Result
AppearanceOff-white to light yellow powderConforms
Deacetylation Degree (D.D.)≥ 90.0%92.5%
ViscosityCustomizable (e.g., 50-200 mPa.s)120 mPa.s
Loss on Drying≤ 10.0%7.8%
Ash≤ 1.0%0.6%
Heavy Metals≤ 10 ppm< 5 ppm
Arsenic (As)≤ 1.0 ppm< 0.2 ppm
Microbiology≤ 1,000 cfu/g< 100 cfu/g
Particle Size100% pass 80 meshConforms

Method of Analysis of Lactoferrin


• Deacetylation Degree: Measured by Potentiometric Titration or H-NMR. This is the most critical parameter determining the product's solubility and charge density.

• Viscosity: Measured using a rotational viscometer (Brookfield) in 1% acetic acid solution.

Reference Chromatogram of Lactoferrin Reference Substance


(Imagine an FT-IR Spectrum)

The FT-IR spectrum shows reduced amide bands (1655 cm-1) and increased amine bands (1590cm-1) compared to Chitin, confirming successful deacetylation.

Stability and Safety


Stability Studies

• Shelf Life: 24 months (2 Years).

• Storage: Store in a cool, dry place. Chitosan is hygroscopic and can absorb moisture from the air; keep bags tightly sealed.

• Solution Stability: Chitosan solutions (in weak acid) are stable but can lose viscosity over time due to slow hydrolysis; prepare fresh for liquid applications.

Safety & Handling (MSDS Summary)

• Classification: Non-hazardous natural polymer.

• Allergen Warning: Derived from Crustaceans (Shellfish). Not suitable for individuals with shellfish allergies. (We also offer fungal-source Chitosan for vegan/allergen-free requests).

• Handling: Standard industrial hygiene.

long-term stability testing of Chitosan

msds of Chitosan

Customer Comments


Production Manager, US Dietary Supplement Co.

Production Manager, US Dietary Supplement Co.

2026.03.03

★★★★★

"Your High-Density Chitosan fills our capsules perfectly. We can fit 500mg into a size 0 capsule, which was impossible with the fluffy material from our previous supplier."
Environmental Engineer, Water Treatment Plant (Spain)

Environmental Engineer, Water Treatment Plant (Spain)

2026.03.03

★★★★★

"Great flocculation performance. We reduced our chemical polymer usage by 30% by switching to your eco-friendly Chitosan."

Our Certificates


CERTIFICATE

CERTIFICATE

CERTIFICATE

CERTIFICATE

FDA

FDA

ISO

ISO

HALAL

HALAL

HACCP

HACCP

Our Clients


Abbott
Big Bear Pharmaceuticals
Spring season
HIEIDO
Oil and Fat Corporation
Dalian University
China Pharmaceutical University
Shenyang Pharmaceutical University
SIOC
SIMM
KANS
Renhe Pharmaceutical
JNJ
HANHOO
Korea University
Kyeonggi University
LG
Samyang Foods
AJINOMOTO
PipingRock‌
DSM-Firmenich
Beijing Tongrentang
Nestlé
BIOHIGH
Evonik Industries
Herbalife Nutrition
L'ORÉAL
STARFIELD
Unilever
MERCK

Exhibitions


• Vitafoods Europe (Geneva)

• CAC (China International Agrochemical & Crop Protection Exhibition)

• SupplySide West (Las Vegas)

FIC Shanghai

FIC Shanghai

FIC2024

FIC2024

CPHI Korea

CPHI Korea

SupplySideWEST Las Vegas

SupplySideWEST Las Vegas

SupplySideWEST 2023

SupplySideWEST 2023

Vitafoods Europe Switzerland

Vitafoods Europe Switzerland

Wagri Guangzhou

Wagri Guangzhou

In-Cosmetics Global

In-Cosmetics Global

SupplySide West (Las Vegas)

SupplySide West (Las Vegas)

SupplySide West (Las Vegas)

SupplySide West (Las Vegas)

CPHI & PMEC China 2025

CPHI & PMEC China 2025

CAC 24th

CAC 24th

CAC Shanghai

CAC Shanghai

CPHI & PMEC 2024

CPHI & PMEC 2024

CPHI & PMEC China Shanghai

CPHI & PMEC China Shanghai

CPHI 2025

CPHI 2025

CPHI 2024

CPHI 2024

CPHI 2023

CPHI 2023

FIC 2022

FIC 2022

FIC 2023

FIC 2023

Vitafoods Europe (Geneva)

Vitafoods Europe (Geneva)

CPhI Worldwide

CPhI Worldwide

FAQ


What viscosity should I choose?

• Low Viscosity (<50 cps): Best for spraying (agriculture) and beverages. • Medium Viscosity (100-500 cps): Ideal for dietary supplements (capsules) and general industrial use. • High Viscosity (>500 cps): Used for gels, films, and medical dressings requiring strong structural integrity.

Is Chitosan soluble in water?

Standard Chitosan is insoluble in neutral water. It dissolves in dilute organic acids (like acetic acid, lactic acid, or citric acid) at pH < 6.0. For water-soluble needs, ask for our Chitosan Oligosaccharide or Carboxymethyl Chitosan.

Do you have a Vegan version?

Yes. While standard Chitosan is from crab/shrimp shells, we also manufacture Fungal Chitosan (from Aspergillus niger), which is 100% non-animal, non-GMO, and allergen-free.

References


1.Rinaudo, M. "Chitin and chitosan: Properties and applications." Progress in Polymer Science (2006).

2.Koide, S. S. "Chitosan: remedial properties and applications." Nutrition (1998).

3.El Hadrami, A., et al. "Chitosan in plant protection." Marine Drugs (2010).

4.Kumar, M. N. R. "A review of chitin and chitosan applications." Reactive and Functional Polymers (2000).

5.Shahidi, F., et al. "Food applications of chitin and chitosans." Trends in Food Science & Technology (1999).

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