Perillartine
Perillartine Manufacturer | High-Intensity Sweetener & Tobacco Flavor (CAS: 30950-27-7) Headline: Premium Perillartine (Perilla Sugar) Manufacturer | 2000x Sweetness (CAS: 30950-27-7) Sub-info: >98% Purity HPLC | Natural Perilla Derivative | Tobacco Smoothing Agent USP: Masks Tobacco Bitterness | High Thermal Stability | Cost-Effective Dosage
Introduction
Perillartine (CAS: 30950-27-7), also known as Perilla Sugar or Perilla Aldehyde Oxime, is a high-intensity sweetener synthesized from Perillaldehyde (extracted from Perilla frutescens). It is renowned for being approximately 2000 times sweeter than sucrose, making it one of the most potent sweetening agents available for industrial applications.
As a specialized manufacturer, we produce Pharmaceutical-Grade Perillartine (99% Purity) specifically optimized for the Tobacco Industry. Unlike common sweeteners, Perillartine offers a unique functional benefit: it masks the harshness of nicotine and tar, significantly upgrading the sensory profile of mid-to-low-grade tobacco leaves without altering the core tobacco aroma.
Category：
Keywords：
tobacco
perillartine
perilla
Functions
Perillartine functions primarily as a sensory modifier and masking agent.
1. Potent Sweetening Power (MOA):
Structurally an oxime of Perillaldehyde, it interacts with sweet taste receptors (T1R2/T1R3) at extremely low concentrations. Its high sweetness potency allows for micro-dosing, which minimizes formulation costs.
2. Smoke Softening & Harshness Reduction:
In tobacco combustion, Perillartine decomposes to release faint, pleasant herbal notes that neutralize the biting, astringent taste of smoke. It "rounds off" the smoke, making the inhalation experience smoother and more delicate.
3. Aftertaste Improvement:
It eliminates the bitter and spicy aftertaste often associated with lower-quality tobacco blends, leaving a clean, slightly sweet mouthfeel.
4. Flavor Stability:
It exhibits excellent thermal stability, ensuring that its sweetening and masking properties survive the high temperatures of cigarette combustion or food processing.
Applications
Tobacco Industry (Primary Application):
• Used as a casing flavor or top dressing for Flue-cured and Blended cigarettes.
• Benefit: Upgrades "C-grade" tobacco leaves to "B-grade" sensory perception, allowing manufacturers to improve margins.
Oral Care:
• Used in toothpastes and mouthwashes to mask the bitterness of surfactants and menthol.
Animal Feed:
• Used as a palatability enhancer (sweetener) to mask bitter minerals or medicines in feed premixes.
Niche Food Flavoring:
• Used in very trace amounts in specific confectioneries (Japan/Asia) for its unique herbal-sweet profile.
Flow Chart
Production Process (Oxime Synthesis):
1.Raw Material Preparation: High-purity Perillaldehyde (extracted from Perilla Oil).
2.Oximation Reaction: Perillaldehyde reacts with Hydroxylamine Hydrochloride under controlled pH.
3.Crystallization: Formation of crude Perillartine crystals.
4.Purification: Recrystallization in Ethanol/Water solvent to remove unreacted aldehyde and by-products.
5.Filtration & Washing: Removal of solvent residues.
6.Drying: Vacuum drying to achieve crystalline powder form.
7.Sieving: Passing through 80-mesh sieve to ensure uniform particle size for blending.
Quality Standard of Lactoferrin
Spec: Perillartine 99% (Food/Tobacco Grade)
| Item | Specification | Result |
| Appearance | White Crystalline powder | Conforms |
| Odor | Characteristic | Conforms |
| Assay (HPLC) | ≥ 99.0% | 99.4% |
| Melting Point | 97°C - 101°C | 99°C-100℃ |
| Ash | ≤ 0.05% | Conforms |
| Volatile content | ≤ 0.3% | 0.14% |
| Heavy Metals | ≤ 10 ppm | < 5 ppm |
| Arsenic (As) | ≤ 1 ppm | < 1 ppm |
| Solubility(20℃) | 1g fully soluble in 20ml 95% ethanol | Conforms |
Method of Analysis of Lactoferrin
• HPLC (High-Performance Liquid Chromatography): We use a C18 column with a Methanol/Water mobile phase to determine assay.
• Why HPLC? Since Perillartine is an oxime derivative, HPLC ensures we differentiate it from the starting material (Perillaldehyde) and verify that the reaction is complete, guaranteeing maximum sweetness potency.
Reference Chromatogram of Lactoferrin Reference Substance
([Placeholders for Image]: The chromatogram displays a single, sharp peak at retention time ~8.5 min. The baseline is clean, indicating no significant organic impurities.)
Stability and Safety
Stability Studies
• Shelf Life: 24 months.
• Storage: Store in a cool, dry place away from light.
• Thermal Stability: Stable up to melting point (~100°C). In tobacco application, it is effective because it volatilizes/decomposes pleasantly upon burning rather than forming acrid compounds.
• Data: 18-month stability tests at 25°C show no significant change in color (remains white) or assay (>98.8%).
Safety & Handling (MSDS Summary)
• Toxicity: Low acute toxicity. Non-toxic at recommended dosage levels.
• Handling: Dust may cause mechanical irritation. Wear dust mask and goggles.
• Storage: Keep container tightly sealed.
Customer Comments
Product Manager, UK Clean Beauty Brand
2026.02.05
★★★★★
Purchasing Director, US Cosmetics Manufacturer
2026.02.05
★★★★★
Our Certificates
SKS-Kosher
CERTIFICATE
CERTIFICATE
ISO9001
ISO22000
FDA
Our Clients
Exhibitions
• World Tobacco Asia
• InterTabac (Dortmund)
• Food Ingredients China (FIC)
FIC2024
SupplySide West (Las Vegas)
Vitafoods Europe (Geneva)
CPhI Worldwide
FIC Shanghai
CPHI & PMEC 2024
CPHI & PMEC China Shanghai
CPHI Korea
In-Cosmetics Global
SupplySideWEST Las Vegas
SupplySideWEST 2023
Vitafoods Europe Switzerland
Wagri Guangzhou
SupplySide West (Las Vegas)
CPHI & PMEC China 2025
CAC 24th
CAC Shanghai
CPHI 2025
CPHI 2024
CPHI 2023
FIC 2022
FIC 2023
FAQ
What is the difference between Squalene and Squalane?
Squalene (with an 'e') is the unsaturated, natural form (C30H50). Squalane (with an 'a') is the hydrogenated, saturated form (C30H62). Squalene has higher antioxidant activity but is less stable; Squalane is extremely stable but lacks the double bonds for ROS scavenging. We supply both.
How do you verify it is not from sharks?
We strictly control our supply chain and use Fermentation or Olive sources. We can provide C14 Radiocarbon Analysis or IRMS data upon request to scientifically prove the non-animal origin.
Is it suitable for sensitive skin?
Yes. Squalene is bio-identical to human sebum, making it one of the most hypoallergenic lipids available. It is safe for sensitive and baby skin formulations.
References
1.Acton, Q. A. (2013). "Aldehydes—Advances in Research and Application: Perillaldehyde and Perillartine."
2.Yamaguchi, K. (1970). "Sweetening potency of Perillartine derivatives." Agricultural and Biological Chemistry.
3.Tobacco Science Research Conference. "Additives for Smoke Harshness Reduction."
4.Merck Index. "Perillartine: Monograph 7120."
5.Joint FAO/WHO Expert Committee on Food Additives (JECFA). "Safety evaluation of certain food additives (Flavoring agents)."
Related Products
Our Global Presence：Pioneer Biotech | Pioneer Bio Inc. | Kono Chem | Kono Chem (RU)
P&K INTERNATIONAL PTE. LTD.